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This product is Paclitaxel albumin bound (Abraxane). Paclitaxel is a natural anti-cancer material which inhibits the process of cell division and growth of cancer cells. This drug uses albumin as carrier of water insoluble molecules in the body which selectively accumulates in tumor tissues. Unlike other solvent based chemotherapy drugs, this drug has no side effects because the effective anti-cancer material, paclitaxel, is placed inside albumin.
Nanoparticles increase drug penetration into the cancerous tissues and improve drug delivery to the tumor.
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This product is SinaDoxosome containing liposomal hydrochloride doxorubicin. Its formulation is in a way that inserts doxorubicin into the nanoliposome carriers and increases permeability and retention of the drug in the tumor tissue. This lipid carrier decreases the side effects of doxorubicin due to the small amount of leakage. In this way cardiac toxicity of the drug that is the most dangerous side effect is significantly reduced. SinaDoxosome is used in the treatment of various cancers and because of the high efficiency of its liposomal nature, it has significant effect on metastatic cancers including metastatic breast, ovarian cancers as well as multiple myeloma and AIDS-related Kaposi’s sarcoma.
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