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ADIPISCING CONVALLIS BULUM
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This product is SinaDoxosome containing liposomal hydrochloride doxorubicin. Its formulation is in a way that inserts doxorubicin into the nanoliposome carriers and increases permeability and retention of the drug in the tumor tissue. This lipid carrier decreases the side effects of doxorubicin due to the small amount of leakage. In this way cardiac toxicity of the drug that is the most dangerous side effect is significantly reduced. SinaDoxosome is used in the treatment of various cancers and because of the high efficiency of its liposomal nature, it has significant effect on metastatic cancers including metastatic breast, ovarian cancers as well as multiple myeloma and AIDS-related Kaposi’s sarcoma.
This product is nano-micelles containing curcumin with the ability to disperse and dissolve in water. Curcumin is poorly absorbed into the body because it is insoluble in water. Therefore, the dissolution of curcumin in an aqueous medium is of great importance. Micelle is a surfactant molecule aggregate dispersed in a liquid colloid. It is a nanosized vesicular membrane which becomes soluble in water by gathering the hydrophilic heads outside in contact with the solvent and hydrophobic tails inside, which is known as emulsification. Loading the curcumin in nano-micelles enhances its dissolution and dispersion in water and helps it to absorb into the body. In general, the most important biological effects of turmeric and curcumin are anti-inflammatory, antioxidant and anti-cancer effects.